Clear VASCEPA® (icosapent ethyl) capsule

The clear choice for reducing cardiovascular (CV) risk

Only VASCEPA has the FDA's stamp of approval for reducing CV risk when added to a statin.

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Cardio protection.
Proven by science.

In a landmark clinical trial involving more than 8,000 eligible patients, VASCEPA was proven and FDA-approved to reduce CV risk when added to a statin.

VASCEPA is the only FDA-approved oral medication that can make this bold statement.

Is there anything more important than heart protection? If you or someone you love has heart disease, or had experienced a previous heart attack or stroke, there is no time to waste. VASCEPA is proven to provide 25% additional heart protection when added to a statin.*

*In a clinical study, patients treated with VASCEPA and a statin had fewer CV events (17.2%) compared to those who took placebo (22%).

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What’s in VASCEPA?

FDA-approved VASCEPA is made up of one active ingredient: icosapent ethyl (IPE), which is an innovative form of eicosapentaenoic acid (EPA)

If “EPA” sounds familiar, that’s because it’s an omega-3 fatty acid. IPE is the only active ingredient in VASCEPA and is considered the reason behind the significant CV benefits VASCEPA can deliver.

How VASCEPA reduces CV risk

VASCEPA is the first and only FDA-approved medication to lower CV risk in addition to other medications, such as statins, in patients with high triglycerides (≥150 mg/dL) and heart disease or diabetes with other CV risk factors. The exact science of how VASCEPA works in your body is not fully understood, but years of clinical testing have led to proven results. Ask your doctor about heart protection with VASCEPA.

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Are you at greater risk than you think?

A closer look at fish oil supplements

When it comes to protecting your heart, learn how fish oil supplements are different from VASCEPA.

Fish oil supplements

  • After reviewing decades of research, the FDA found fish oil supplements do not meet the standard required for a significant scientific health claim
  • Contain a mixture of ingredients that may be harmful to heart health, and may have a pronounced fishy smell or require smell masking to hide the signs of deterioration/oxidation (rotting)
  • Not intended or approved to treat heart disease
  • The American Heart Association advises against self-medicating with supplements
  • The most expensive product is one that doesn't treat the intended condition


  • Proven CV benefit in the landmark REDUCE-IT® trial
  • Made up of one active ingredient: IPE (icosapent ethyl), an innovative form of EPA
  • FDA approved to significantly reduce CV risk in patients taking statins. If you cannot take statins, talk to your doctor about whether or not VASCEPA can help you
  • Recognized by medical societies to lower CV risk in patients with heart disease or diabetes and risk factors

When it comes to protecting your heart, the choice is clear: FDA-approved VASCEPA

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Talk to your doctor about CV risk reduction

As you discuss with your doctor or pharmacist if VASCEPA may be right for you to reduce your CV risk, the subject of generic alternatives to VASCEPA may come up.

Between insurance coverage, Medicare Part D, and the VASCEPA Savings Card (see offer below), you may find that VASCEPA is actually cheaper than a generic. If you have any questions or concerns about cost, make sure to contact your insurance company.

VASCEPA® (icosapent ethyl) savings card

Looking for ways to save on VASCEPA?

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VASCEPA is FDA-approved to help protect you from a life-threatening heart attack or stroke. Is VASCEPA right for you?




VASCEPA is a prescription medicine used:

  • along with certain medicines (statins) to reduce the risk of heart attack, stroke and certain types of heart issues requiring hospitalization in adults with heart (cardiovascular) disease, or diabetes and 2 or more additional risk factors for heart disease.
  • along with a low-fat and low-cholesterol diet to lower high levels of triglycerides (fats) in adults.

It is not known if VASCEPA changes your risk of having inflammation of your pancreas (pancreatitis).
It is not known if VASCEPA is safe and effective in children.



  • Do not take VASCEPA if you are allergic to icosapent ethyl or any of the ingredients in VASCEPA.

What are the possible side effects of VASCEPA?
VASCEPA may cause serious side effects, including:

  • Heart rhythm problems (atrial fibrillation and atrial flutter). Heart rhythm problems which can be serious and cause hospitalization have happened in people who take VASCEPA, especially in people who have heart (cardiovascular) disease or diabetes with a risk factor for heart (cardiovascular) disease, or who have had heart rhythm problems in the past. Tell your doctor if you get any symptoms of heart rhythm problems such as feeling as if your heart is beating fast and irregular, lightheadedness, dizziness, shortness of breath, chest discomfort or you faint.
  • Possible allergic reactions if you are allergic to fish or shellfish. Stop taking VASCEPA and tell your doctor right away or get emergency medical help if you have any signs or symptoms of an allergic reaction.
  • Bleeding. Serious bleeding can happen in people who take VASCEPA. Your risk of bleeding may increase if you are also taking a blood thinner medicine.
If you have liver problems and are taking VASCEPA, your doctor should do blood tests during treatment.
The most common side effects of VASCEPA include:
  • Muscle and joint pain
  • Swelling of the hands, legs, or feet
  • Constipation
  • Gout
  • Heart rhythm problems (atrial fibrillation)
These are not all the possible side effects of VASCEPA. Call your doctor for medical advice about side effects. You may report adverse events (i.e. side effects) or product complaints by contacting AmarinConnect at 1-855-VASCEPA (1-855-827-2372), emailing [email protected], or calling the FDA at 1-800-FDA-1088.

Tell your doctor if you take medicines that affect your blood clotting (anticoagulants or blood thinners).

For more information on VASCEPA, click here to see the full Patient Information or call 1-855-VASCEPA (1-855-827-2372).